×
Please select City And Area.
Best Doctor List Near You for Chordoma In Orthopedic Surgery in Sao bernardo do campo
Best psoriasis doctors near me
Chordoma is a rare type of malignant bone tumor that primarily arises from the remnants of the notochord, a structure that contributes to the development of the spinal column and the vertebral bodies during embryonic stages. These tumors most commonly occur in the axial skeleton, particularly at the base of the skull and in the sacrococcygeal region, but can also manifest in the thoracic and lumbar spine. While chordomas are often slow-growing, they are notorious for being locally aggressive and can invade surrounding structures, leading to significant morbidity. The exact cause of chordoma remains unclear; however, genetic mutations, particularly involving the Brachyury gene, are believed to play a crucial role in their development. This gene is a crucial transcription factor involved in notochord formation and is often found to be overexpressed in chordoma tissues. In terms of demographics, chordomas are more frequently diagnosed in adults, typically between the ages of 30 and 60, with a slight male predominance. Symptoms of chordoma depend on the tumor's location and size; for example, sacral chordomas may cause lower back pain, altered bowel habits, and neurological deficits due to compression of nearby structures, while cranial chordomas may present with headaches, vision problems, or cranial nerve dysfunction. Diagnosis involves imaging techniques such as MRI or CT scans, which can reveal the characteristic features of a chordoma, including its aggressive growth pattern and involvement of adjacent tissues. A biopsy is often necessary to confirm the diagnosis, as the histological appearance of chordomas is distinctive, featuring a mix of physaliferous cells and a myxoid stroma. Treatment for chordoma typically involves surgical resection, with the goal of achieving clear margins to reduce the likelihood of recurrence. However, complete resection can be challenging due to the tumor's invasive nature and its location near critical structures. In cases where surgical margins cannot be achieved, adjuvant radiation therapy, including proton beam therapy or conventional radiation, may be utilized to target residual tumor cells. Despite treatment, chordomas can recur, and long-term surveillance is essential for early detection of recurrence. The prognosis for chordoma patients varies, with survival rates generally being lower compared to more common bone tumors, often reflecting the tumor's location and the extent of surgical resection. Recent advancements in genetic and molecular research hold promise for more targeted therapies and improved outcomes in the future. Overall, chordoma remains a complex challenge in the field of orthopedic surgery, requiring an interdisciplinary approach for optimal management and care of affected individuals.
- Osteopathic Manipulative Treatment (OMT) Specialist in Sao bernardo do campo
- Endodontics in Sao bernardo do campo
- Oral And Maxillofacial Surgeon in Sao bernardo do campo
- Periodontics in Sao bernardo do campo
- Mohs Surgery in Sao bernardo do campo
- Physical Therapist in Sao bernardo do campo
- Addiction Medicine Specialist in Sao bernardo do campo
- Head and Neck Oncologist in Sao bernardo do campo
- Heart Failure Specialist in Sao bernardo do campo
- Family Physician in Sao bernardo do campo
- Stereotactic Radiosurgery (SRS) Specialist in Sao bernardo do campo
- Neurohormonal Specialist in Sao bernardo do campo
- Anesthesiologist in Sao bernardo do campo
- Diabetic Foot Care Specialist in Sao bernardo do campo
- Sports Medicine Specialist in Sao bernardo do campo
- Maternal Fetal Medicine Specialist in Sao bernardo do campo
- Congenital Heart Disease Specialist in Sao bernardo do campo
- Critical Burn Care Specialist in Sao bernardo do campo
- Spine Reconstruction Surgeon in Sao bernardo do campo
- HIV/AIDS Specialist in Sao bernardo do campo
- Telepsychiatry in Sao bernardo do campo
- Micropore Particle Technology in Sao bernardo do campo
- Cereblon E3 Ligase Modulators in Sao bernardo do campo
- Hydradermabrasion in Sao bernardo do campo
- Pastille in Sao bernardo do campo
- Ureteroureterostomy in Sao bernardo do campo
- Oronasal Fistula Repair in Sao bernardo do campo
- Phalloplasty in Sao bernardo do campo
- Neuroendoscopy in Sao bernardo do campo
- Mtp (Medical Termination Of Pregnancy) in Sao bernardo do campo
- Stemless Shoulder Arthroplasty in Sao bernardo do campo
- Nail Avulsion in Sao bernardo do campo
- Rastelli Procedure in Sao bernardo do campo
- Telangiectatic Osteosarcoma in Sao bernardo do campo
- Laparoscopic Supracervical Hysterectomy in Sao bernardo do campo
- Turbinectomy in Sao bernardo do campo
- Wrist Reconstruction in Sao bernardo do campo
- Myringoplasty (Eardrum Repair) in Sao bernardo do campo
- Nuclear Medicine Scans in Sao bernardo do campo
- Elbow Arthroplasty in Sao bernardo do campo
- Immunotherapy in Sao bernardo do campo
- Earlobe Reduction Surgery in Sao bernardo do campo
- Rehabilitation and Follow-Up in Sao bernardo do campo
- Gastrointestinal Radiology Services in Sao bernardo do campo
- Endoscopic Neurosurgery in Sao bernardo do campo
- End-of-Life Care in Sao bernardo do campo
- Criminal Competency Evaluations in Sao bernardo do campo
- Long-Term Monitoring and Follow-Up in Sao bernardo do campo
- Cardiac MRI and CT Scans in Sao bernardo do campo
- Customized Physical and Occupational Therapy in Sao bernardo do campo
- Vacuum-Assisted Closure (VAC) Therapy in Sao bernardo do campo
- Alternative and Complementary Therapies in Sao bernardo do campo
- Ambulance Services in Sao bernardo do campo
- Hand Surgery Services in Sao bernardo do campo
- Newborn Care Services in Sao bernardo do campo
- Oncologic (Cancer) Scans in Sao bernardo do campo
- Vagus Nerve Stimulation (VNS) in Sao bernardo do campo
- Geriatric Nutritional Support in Sao bernardo do campo
- Orthopedic Rehabilitation in Sao bernardo do campo
- Clinical Immunology in Sao bernardo do campo
- Pediatric Endoscopic Procedures in Sao bernardo do campo
- Pediatric Sleep-Related Breathing Disorders in Sao bernardo do campo
- Drug Safety Testing in Sao bernardo do campo